Please note: We are not currently accepting additional applicants into this program.
graduate certificate in Laboratory and Biological Safety is one
of the few academic credit programs in biosafety available in
the United States today.
By making this certificate program
available to students entirely online, the University of
Massachusetts Lowell is providing an affordable, accessible way
for individuals to enter the field of biological and laboratory
safety. The program is designed to provide certificate
candidates with the principles of identification, evaluation and
control of biological and laboratory hazards. Topics include
basic occupational health and safety including chemical and
ergonomic hazards, biological hazard risk assessment,
disinfection and sterilization, aerobiology, laboratory
environmental health and safety management, laboratory design,
laboratory hood requirements and many other subjects.
Scientists responsible for biological and/or laboratory safety, occupational & environmental hygienist
and those interested in embarking upon a career in biological and/or laboratory safety.
All applicants must have already completed their bachelor's degree,
preferably in a life sciences discipline, from an accredited
institution of higher education, and have taken at least
three undergraduate-level biology courses such as Microbiology, Cell
Biology, and/or Molecular Biology or Biochemistry, or have
significant work experience in biosafety (permission of the program
coordinator required), prior to applying into the program.
- PUBH.5080 Principles and Practices of Biological Safety
- PUBH.5160 Laboratory Environmental Health and Safety
- PUBH.5250 Introduction to Occupational & Environmental Hygiene & Ergonomics
Electives (choose 1):
- MLSC.5410 Introduction to Public Health and the Public Health Laboratory
- HSCI.5500 Human Development and Pathophysiology
- MLSC.5800 Clinical Applications of Molecular Genetics
- 32.504 Health Data Analysis
For program-specific questions, please contact Professor Susan
Woskie, Ph.D., CIH and Graduate Biosafety Program Coordinator at
(978) 934-3295 or email her at
Gainful Employment Disclosure Information
Completion rates, median loan debts and program costs are outlined for
each certificate program.
Graduate Certificate Gainful Employment Disclosure Information
32.504 Health Data Analysis
This course focuses on the application of both descriptive and inferential statistical techniques to the analysis of health care data. Students will learn how to a) formulate research questions and hypotheses answerable through quantitative data analysis, b) use computer software (Statistical Package for The social Sciences, SPSS) and an online Probability Calculator to analyze data, and c) interpret the meaning of statistical findings. Areas covered include graphs, measurement, normal distribution, hypothesis testing, t tests, ANOVA, correlation and regression, and chi-square. Emphasis is on using weekly SPSS assignments to analyze research questions using a sample data base from the Framingham Heart Study. Prerequisite: an elementary statistics course. 3 credits.
Prerequisite: An elementary statistics course
HSCI.5500 Human Development and Pathophysiology
The physiological steady state of the human body and disruptions that result over the life span will be examined as well as the pathophysiological mechanism manifested in disease states. The course addresses defense, compensating, and adaptive responses to the pathophysiological processes as they apply to the various systems rather than being a survey course of diseases. 3 credits.
MLSC.5410 Introduction to Public Health and the Public Health Laboratory
This course is designed to provide an overview
of public health and the public heath
laborabory covering topics such as the legal
basis and history of public health, public
health structure, communications and
interactions, and epidemiology. Emphasis will
be placed on the role of the public health
laboratory and its core functions, its role in
policy development, infectious disease,
environmental issues, emergency preparedness,
newborn screening, global issues, and public
health research. Public health laboratory
methodology, regulation and improvement, and
quality assurance will also be examined. 3 credits.
Prerequisite: MS in Clinical Lab Sciences
MLSC.5800 Clinical Applications of Molecular Genetics
This course begins with a review of basic molecular genetics, followed by a discussion of the human genome project, including the application of its technology to the management of genetic diseases. Laboratory techniques used to analyze pre- and postnatal tissue samples is described, including RFLP-Southern blot technology, various forms of PCR, VNTR assessment, and gene expression analysis by microchip arrays. Cloning and stem cell analysis follows, including the ethical, legal, and social issues surrounding these areas. Cancer genetics and cytogenesis is presented, with emphasis on molecular changes that lead to the onset of cancer. Genetic treatments for cancer are reviewed. Gene therapy is detailed, including the historical perspective, gene therapy vectors and their mode of action, and the newest methods for treating genetic disorders at the DNA level. Structural and functional genomics follows, centering around the creation of pharmaceuticals solely based on the genetic basis of diseases. This is followed by a detailed section on epigenetics and its application to diagnosis and prediction of disease phenotypes. GWAS (Genome Wide Association Studies) is detailed as it applies to diagnosis in both individuals and entire populations. The course ends with a discussion of the human proteome project, and the human transcriptome project, including goals and objectives, current progress, and the storage of data in complex bioinformatic databases. 3 credits.
Prerequisite: CSCE Graduate Restrictions
PUBH.5080 Principles and Practices of Biological Safety
This course is designed to provide an overview of hazard recognition, evaluation and control of potentially hazardous biological materials. This introduction to the field will cover the potential risks of working with biological materials, the use of engineering, work practices and administrative measures for hazard control and regulations governing the area of biosafety. Requires working knowledge of Microbiology, and permission of Instructor. 3 credits.
Special Notes: Requires working knowledge of Microbiology, and permission of Instructor.
PUBH.5160 Laboratory Environmental Health and Safety
This course is designed to provide an overview of hazard recognition, evaluation and control in laboratory environments. This introduction to the field will cover the potential risks of working with chemicals, radioactive materials, animals and biological materials. It will also introduce the use of engineering, workpractices and administrative measures for hazard control and regulations governing the area of laboratory safety. 3 credits.
PUBH.5250 Introduction to Occupational & Environmental Hygiene & Ergonomics
A survey course covering introductory topics in ergonomics and industrial hygiene. Ergonomics topics include work measurement, anthropometry, biomechanics, psychosocial stress and work reorganization, special emphasis is placed on the recognition and control of work-related musculoskeletal disorders. Industrial hygiene topics will cover the identification, measurement, and control of chemical and physical hazards in the work environment including principles of air sampling and analysis, ventilation and other control technologies, and the use of personal protective equipment with special attention to respiratory and hearing protection. 3 credits.