Nanoemulsions: Recent Advances in Synthesis, Properties and Applications

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3 DAY LECTURE/WORKSHOP
OFFERED ONCE:
August 9-11, 2010 (CRS# 00.739-021)
8:30am-5:00pm

TUITION: $1195

OVERVIEW
A four-day course covering the fundamental concepts important in the manufacture, characterization and application of nanoemulsions polymer latexes. Topics include colloidal stability, formulation of nanoemulsions, polymerization kinetics and mechanisms, characterization of particle surfaces, nanoemulsion polymer latex properties specific to rheology, morphology, polymerization with functional groups, and film formation. Nanoemulsions can be defined as oil-in-water (o/w) emulsions with mean droplet diameters ranging from 50 to 1000 nm. Usually, the average droplet size is between 100 and 500 nm. The terms sub-micron emulsion and miniemulsion are used as synonyms. Emulsions which match this definition have been used in parenteral nutrition for a long time. Usually, nanoemulsions contain 10 to 20 percent oil stabilized with 0.5 to 2 percent egg or soybean lecithin. A typical formulation is given in Table 1

CONTENT
The preparation of nanoemulsions requires high-pressure homogenization. The particles which are formed exhibit a liquid, lipophilic core separated from the surrounding aqueous phase by a monomolecular layer of phospholipids. The structure of such lecithin stabilized oil droplets can be compared to chylomicrons. Nanoemulsions therefore differ clearly from the liposomes, where a phospholipid bilayer separates an aqueous core from a hydrophilic external phase (see Figures 1 and 2). If nanoemulsions are prepared with an excess of phospholipids, liposomes may occur concurrently. Systems of particular relevance in formulating paints, industrial coatings, inks, cosmetics, pharmaceutical and biomedical applications problems will be reviewed.

INSTRUCTOR
Dr. Bridgette Budhlall